Université PSL


Date : 08/12/2019 - 1 pm-2.30 pm
Lieu : IPGG

Artificial memories in mice - How and why we create them

he search for the neuronal code that the brain uses to process information that we receive from the external world is one of the most fascinating and challenging field in neuroscience. The use of cutting edge technologies created by the collaboration between bioengineers and neuroscientists introduced a scientific revolution in this field. We can now modulate specific subpopulation of neurons in real time and study their contribution to cognitive processes, like the formation of memories. Most importantly, we are now able to investigate and answer fundamental questions about the brain functions, such as: is there a code the brain uses to process external information? Are there specific patterns of neuronal activity encoding a memory trace to recall it later in time? Can we create artificial memories? ln this seminar, 1 will present the possibility to implant fully artificial memories in mice by substituting the external experience with the optogenetic stimulation of specific neuronal ensembles in the brain. 1 will also explain the brain ability to continuously integrate new information into the existing neuronal network by changing its own functional structure.