Computational biologist

Déposé le : 25/06/2018
Localisation : 75005
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Descriptif du poste :
Careers in HiFiBiO
2 July 2018

Computational biologist in Single-Cell Therapeutics Discovery – Paris, France

HiFiBiO Therapeutics ( is an emerging multinational biotherapeutics company mobilizing the human immune system to combat disease. The company integrates deep-rooted biological expertise with our comprehensive single-cell profiling technologies to rapidly discover and advance a pipeline of antibody drugs to treat cancer and autoimmune disorders. In addition, HiFiBiO Therapeutics aspires to benefit patients through open-innovation partnerships with industry and academia. The combination of scientific leadership, exclusive IP and an experienced management team
provides the company with a unique opportunity to introduce a breakthrough single-cell screening technology in the field of drug discovery, target- and biomarker discovery.

We are looking for enthusiastic, innovative people who share our passion to build – together with world leading pharmaceutical companies - THE next generation of therapeutics and development technologies using leading edge technologies from ESPCI, Harvard and the Broad Institute. You will work in a dynamic, young company with an experienced management team and support of a scientific founding team that are recognized global leaders in our core technologies.

The following position is open now for our lab facility in Paris:
Senior Scientist, PhD in Bioinformatics
 Job requirement:
o The candidate is an innovator, bringing novel, creative ideas into an industrial reality
o The candidate must have excellent organizational skills in the key areas of computational biology/ with the expectation she/he will coordinate with
engineers and advisors to implement and validate single cell microdroplet assays developed internally or in collaboration with HiFiBiO
o The candidate will contribute to bioinformatics analysis, development and deployment to general users for pre-clinical and clinical purposes;
participate in the formulation and execution of a technical plan to meet our requirements.
o The candidate must have good written and oral communication skills; be able to communicate and work collaboratively with other team members
to an interdisciplinary team.
o The candidate must be a self-starter; be able to work collaboratively and to work to deadlines and deliver a quality result is a must.
o The candidate must demonstrate ability to participate in cross-functional, global teams.
 Essential duties and responsibilities:
o Learn and optimize single cell bioinformatics pipelines adapted to single cell droplet-based microfluidics assays on an industrial & robust level
o Lead all bioinformatics operations, R&D and implementations.
o Team player, ability to work with engineers and wet lab scientists.
 Preferred experience:
o Extensive experience in analyzing high-throughput sequencing data such as RNA-seq, ChIP-seq, WGS etc.
o Good knowledge of molecular biology, mammalian gene expression and preferably immunology
o Experience analyzing single-cell datasets
o Proficient understanding of statistics
o Extensive knowledge of scripting language like Perl, Python, database SQL, graphing and statistical analyses in R and shell scripting in Linux
o Experience in working with industrial partners and with sub-contractors
 Working w/ partners to define their needs
 Formulating a technical plan in response to needs & requirements
 Executing on the technical plan and presenting the results
 Education requirements / working experience:
o PhD in Bioinformatics with >3 years industry experience preferred or 3 years post-doctoral position.
o Excellent oral, written and presentation skills in English

Contact: Dr. Annabelle Gérard, Director
To apply, please send a cover letter briefly stating why your skills set would suit the job and your reasons for applying as well as your CV to Annabelle Gérard. The position will remain open until it is filled and is available to start straight away.

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